Genomic Community Resources (U24 Clinical Trial Not Allowed) | PAR 23 124

Opportunity Information: Apply for PAR 23 124

The Genomic Community Resources (U24 Clinical Trial Not Allowed) opportunity, announced by the National Institutes of Health through the National Human Genome Research Institute (NHGRI), is designed to strengthen the shared infrastructure that makes modern genomics research possible. Its core aim is to accelerate genomic discovery by funding resources that are broadly useful to the biomedical research community and by ensuring those resources and their outputs are widely disseminated. The program supports both the creation of new community resources and the continuation or expansion of existing resources, as long as they have clear, demonstrated value to a wide user base rather than serving only a narrow project or single lab.

Awards are made as U24 cooperative agreements, which generally means the funded work is expected to be high-impact, community-facing, and carried out with substantial scientific and programmatic involvement from NIH staff compared with a standard research grant. The “Clinical Trial Not Allowed” designation signals that the proposed activities should not include prospective clinical trial research; the focus is on building and distributing tools, datasets, standards, repositories, and other enabling resources that can support both basic genomics and clinically relevant genomics research downstream without the award itself being structured as a clinical trial.

The types of resources NHGRI is looking to support span several major categories. One is genomic informatics toolsets, including software, analysis pipelines, and foundational knowledge structures such as biomedical ontologies that help researchers describe, integrate, and analyze genomic and phenotypic data consistently. Another is comprehensive identification and curated collections of genomic features, which can include resources that catalog functional genomic elements or aggregate genetic assay results in ways that are standardized, searchable, and reusable by the broader community. The announcement also emphasizes genomic community-building efforts, such as developing and promoting standards that improve interoperability, data quality, and reproducibility across labs and platforms. In addition, it supports sample repositories that enable high-value genomic studies, for example repositories of cell lines or other well-characterized biological materials that can be distributed for research use.

Eligibility is broad and includes many common public and private research-performing organizations: state, county, city, and special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations that are not federally recognized tribal governments. The opportunity is also open to nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including those other than small businesses), and small businesses, as well as “other” organization types. The listing explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This wide eligibility aligns with the program’s goal of supporting resources meant for broad community benefit, regardless of where the expertise or unique materials reside.

Administratively, this is a discretionary funding opportunity under NIH, with activity categories listed as education and health, and it is associated with CFDA numbers 93.172 and 93.399. The funding opportunity number is PAR 23 124, and the original closing date provided is 2026-01-25. An award ceiling is not specified in the provided source data, and the expected number of awards is not listed, which typically means applicants should rely on the full FOA text and NIH guidance for budget expectations, scope alignment, and review considerations.

Overall, the opportunity is best understood as support for shared genomic infrastructure: tools, datasets, standards, and repositories that many researchers can use, that are maintained and distributed responsibly, and that measurably advance the capacity and efficiency of the genomics field as a whole.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Genomic Community Resources (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172, 93.399.
• This funding opportunity was created on 2023-03-01.
• Applicants must submit their applications by 2026-01-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 23 124

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