Opportunity Information: Apply for RFA CE 22 012
The CDC National Centers of Excellence in Youth Violence Prevention (YVPCs) funding opportunity (RFA CE 22 012) is a cooperative agreement released by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC). Its central goal is to expand the national evidence base on what truly works to prevent and reduce community violence involving youth and young adults ages 10 to 34. Rather than funding broad, general programming, the announcement is designed to support a small number of place-based Centers of Excellence that will implement and rigorously evaluate violence prevention strategies in real communities where youth violence is measurably higher than the national average and where multiple well-established risk factors are present.
A defining feature of this opportunity is its emphasis on geographically defined communities with high rates of youth violence. Applicants are expected to anchor all major activities in one community, or a set of connected communities, where violence is a demonstrated and urgent problem. The CDC is looking for proposals that do not just describe need in abstract terms, but that are rooted in local data and a clear understanding of community conditions. The overall expectation is that the funded YVPCs will partner locally, implement prevention approaches in context, and produce credible findings that help other communities and decision-makers understand which strategies reduce violence at a community level.
The program requires strong community engagement, including the formation of a youth advisory council. This is not presented as a symbolic add-on; the youth advisory council is intended to provide meaningful input into the selection, implementation, and evaluation of prevention strategies. In practice, this means youth perspectives should help shape what gets prioritized, how interventions are delivered, and what outcomes matter, which aligns with the reality that sustainable violence prevention work is stronger when it is informed by people most affected by the issue.
A core requirement is rigorous evaluation. Each funded YVPC must conduct a rigorous evaluation of at least two distinct prevention strategies. Those strategies must align with at least two of the four research areas described in the Notice of Funding Opportunity (NOFO). While the summary text does not list the four areas explicitly, the structure makes the intent clear: CDC wants centers to test more than one approach, and to build evidence across multiple dimensions of prevention rather than relying on a single intervention. The focus is on strategies designed to reduce community rates of youth violence, meaning evaluations should be capable of linking interventions to measurable changes in violence outcomes, not only intermediate measures like knowledge or attitudes.
Beyond implementation and evaluation, the opportunity places weight on organizational capacity and collaboration. Applicants are expected to establish an administrative infrastructure that can support day-to-day operations and the more complex tasks tied to high-quality evaluation, dissemination of results, and long-term sustainability planning. The CDC also emphasizes the importance of fostering local collaborations, reflecting the reality that youth violence prevention typically requires coordination across sectors such as public health, education, social services, law enforcement, community-based organizations, and local government. Funded centers will also be expected to work with other awardees as part of a broader YVPC Network, suggesting shared learning, common standards where appropriate, and coordinated efforts to grow the field.
Another important component is workforce development. This NOFO supports YVPCs in training early career and junior researchers in youth violence prevention. The intent is to strengthen the pipeline of researchers who can carry forward prevention science, especially research that is community-engaged and evaluation-driven. That training element is meant to complement the center's on-the-ground prevention work and help ensure the investment has longer-term impact beyond the immediate project period.
In terms of funding and logistics, the award mechanism is a cooperative agreement, which typically indicates substantial involvement from CDC in the funded work compared with a standard grant. The posted award ceiling is $1,200,000, with an estimated six awards expected. The CFDA number listed is 93.136, and the activity category is health. The opportunity was created on January 12, 2022, with an original closing date of April 18, 2022, and electronic submissions were due by 5:00 pm ET on the deadline. Eligibility is broad and includes various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and other entities as clarified in the eligibility text.
Overall, this opportunity is designed for applicants that can combine strong local partnerships, credible and rigorous evaluation expertise, and the operational capacity to run a center-level effort. The CDC is clearly prioritizing proposals that will generate actionable, transferable evidence about multiple prevention strategies in high-burden communities, while also building infrastructure, strengthening collaboration through a national network, and developing the next generation of youth violence prevention researchers.Apply for RFA CE 22 012
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "The CDC National Centers of Excellence in Youth Violence Prevention (YVPCs): Rigorous Evaluation of Prevention Strategies to Prevent and Reduce Community Rates of Youth Violence" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
- This funding opportunity was created on Jan 12, 2022.
- Applicants must submit their applications by Apr 18, 2022 Electronically submitted applications must be submitted no later than 500#160pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,200,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs): CDC National Centers of Excellence in Youth Violence Prevention (YVPCs) - RFA CE 22 012
1) What is the CDC YVPC funding opportunity (RFA CE 22 012)?
This funding opportunity supports the CDC National Centers of Excellence in Youth Violence Prevention (YVPCs). It is a cooperative agreement released by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC).
2) What is the main goal of the YVPC program?
The central goal is to expand the national evidence base on what works to prevent and reduce community violence involving youth and young adults ages 10 to 34. The program is designed to generate credible findings about prevention strategies that can help inform other communities and decision-makers.
3) Who is the focus population for this program?
The focus is on youth and young adults ages 10 to 34, specifically in the context of preventing and reducing community violence that affects this age range.
4) Is this opportunity meant to fund broad or general violence prevention programming?
No. The announcement is designed to fund a small number of place-based Centers of Excellence that implement and rigorously evaluate violence prevention strategies in real communities where youth violence is measurably higher than the national average and multiple well-established risk factors are present.
5) What does "place-based" mean in this opportunity?
Place-based means applicants are expected to anchor major activities in one geographically defined community, or a set of connected communities, where youth violence is a demonstrated and urgent problem. The CDC is prioritizing proposals rooted in local data and a clear understanding of local community conditions.
6) What kind of communities does CDC want applicants to focus on?
The opportunity emphasizes geographically defined communities with high rates of youth violence compared with the national average, and where multiple well-established risk factors are present. Applicants are expected to demonstrate need using local data rather than relying on abstract descriptions.
7) What are applicants expected to do in the selected community?
Funded centers are expected to partner locally, implement youth violence prevention approaches in context, and produce credible findings that help others understand which strategies reduce violence at a community level.
8) How important is community engagement in this program?
Community engagement is a major requirement. The program description highlights strong community engagement as an expectation, including meaningful youth involvement through a youth advisory council.
9) Is a youth advisory council required?
Yes. The program requires formation of a youth advisory council, and it is intended to be a meaningful mechanism for youth input rather than a symbolic add-on.
10) What role is the youth advisory council expected to play?
The youth advisory council is intended to provide meaningful input into the selection, implementation, and evaluation of prevention strategies. This includes shaping priorities, influencing how interventions are delivered, and informing which outcomes matter.
11) What are the evaluation requirements for a funded YVPC?
Each funded YVPC must conduct a rigorous evaluation of at least two distinct prevention strategies. The evaluations are expected to be capable of linking interventions to measurable changes in violence outcomes, not only intermediate measures such as knowledge or attitudes.
12) How many prevention strategies must be evaluated?
At least two distinct prevention strategies must be implemented and rigorously evaluated by each funded center.
13) Do the prevention strategies need to align with specific research areas?
Yes. The strategies must align with at least two of the four research areas described in the Notice of Funding Opportunity (NOFO). The summary information does not list the four areas explicitly, but it states that alignment with at least two of them is required.
14) What outcomes should the strategies aim to affect?
The focus is on strategies designed to reduce community rates of youth violence. The expectation is that evaluation approaches will be able to connect strategies to measurable changes in violence outcomes at the community level.
15) What kind of organizational capacity is expected from applicants?
Applicants are expected to establish administrative infrastructure to support day-to-day operations and more complex responsibilities tied to evaluation, dissemination of results, and long-term sustainability planning.
16) Are partnerships and cross-sector collaboration part of the program expectations?
Yes. The CDC emphasizes fostering local collaborations, reflecting that youth violence prevention often requires coordination across sectors such as public health, education, social services, law enforcement, community-based organizations, and local government.
17) What is the YVPC Network mentioned in the opportunity?
Funded centers are expected to work with other awardees as part of a broader YVPC Network. The description suggests shared learning, coordinated efforts to grow the field, and common standards where appropriate.
18) Does the program include workforce development or training requirements?
Yes. The NOFO supports YVPCs in training early career and junior researchers in youth violence prevention. The intent is to strengthen the pipeline of researchers focused on community-engaged, evaluation-driven prevention science.
19) What is the funding mechanism for this opportunity?
The award mechanism is a cooperative agreement, which typically indicates substantial involvement from CDC in the funded work compared with a standard grant.
20) What is the award ceiling for this opportunity?
The posted award ceiling is $1,200,000.
21) How many awards are expected?
The opportunity estimates approximately six awards.
22) What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.136.
23) What is the activity category for this opportunity?
The activity category is health.
24) When was this opportunity created and when did it close?
The opportunity was created on January 12, 2022. The original closing date was April 18, 2022, with electronic submissions due by 5:00 pm ET on the deadline.
25) Who is eligible to apply?
Eligibility is broad and includes various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and other entities as clarified in the eligibility text.
26) What kinds of applicants are a good fit for this opportunity?
This opportunity is designed for applicants that can combine strong local partnerships, credible and rigorous evaluation expertise, and the operational capacity to run a center-level effort. The CDC is prioritizing proposals that generate actionable, transferable evidence about multiple prevention strategies in high-burden communities while supporting collaboration and workforce development.
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